Malate-aspartate shuttle　　　　　　

　AST (GOT) participates in malate-aspartate shuttle.
　Malate-aspartate shuttle is necessary for oxaloacetate transportation form mitochondrial matrix to cytosol.
　Pyruvate, lactate, and amino acid (ex. alanin) are used for gluconeogenesis.
　But, note that fatty acids are not used for gluconeogenesis.

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　Key Words :
　Acyl-CoA, α-ketoglutarate, Alanin, Aspartate, β-oxidation cycle,
　Citrate, Citrate sunthase, Fatty acids,
　GDH, Gluconeogenesis, Glucose, Glutamate, Glycolysis, Glutamate-aspartate transporter,
　Kreb's citric acid cycle, Lactate, LDH,
　Malate, Malate-α-ketoglutarate transporter, Malate-aspartate shuttle, MDH,
　NAD⁺, NADH₂⁺,
　Oxaloacetate, PEPCK, Phosphoenolpyruvate,
　Pyruvate, Pyruvate carboxylase, Pyruvate dehydrogenase, Pyruvate kinase,
　ALT(GPT), m-AST (m-AST), s-AST (s-GOT),